Constituents of Mallotus nepalensis Muell. Arg.: a mild CNS depressant
| Publication Type | Journal Article |
| Year of Publication | 2004 |
| Authors | Subha Rastogi,; Mehrotra, B, N.; Kulshreshtha, D, K. |
| Journal Title | Natural Product Sciences |
| Volume | 10 |
| Pagination | 237-239 |
| ISBN Number | 1226-3907 |
| Key Words | central nervous system; chemical composition; medicinal plants; non-wood forest products; pharmacology; phytosterols; plant; composition; plant extracts; ursolic acid; Mallotus (Euphorbiaceae); rats |
| Abstract | M. nepalensis (Euphorbiaceae) is a small tree found in central and eastern Himalayas, Nepal, Wallich and Sikkim. The 90% ethanolic extract of M. nepalensis (collected from Bomdila, West Kameng, Arunachal Pradesh, India) exhibited mild central nervous system depressant activity in rats. Four compounds, lupeol (1), β-sitosterol (2), ursolic acid (3) and β-sitosterol-β-D-glucoside (4) were isolated from the 90% ethanolic extract of this plant of which 1, 3 and 4 are being reported for the first time from this species. |
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