| Abstract | M. nepalensis (Euphorbiaceae) is a small tree found in central and eastern Himalayas, Nepal, Wallich and Sikkim. The 90% ethanolic extract of M. nepalensis (collected from Bomdila, West Kameng, Arunachal Pradesh, India) exhibited mild central nervous system depressant activity in rats. Four compounds, lupeol (1), β-sitosterol (2), ursolic acid (3) and β-sitosterol-β-D-glucoside (4) were isolated from the 90% ethanolic extract of this plant of which 1, 3 and 4 are being reported for the first time from this species. |